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Sunday, September 26, 2010
Title: Changing Clinical Situation: From PPROM to HELLP
Discipline: Childbearing (CB)
Learning Objectives:
Submission Description:- Discuss the incidence and risk factors of the gravid patient developing acute renal failure.
- Explain the pathophysiology of preeclampsia, HELLP and acute renal failure in the gravid patient.
- Discuss a complicated obstetrical case of a gravid patient presenting with PPROM who subsequently develops preeclampsia, HELLP and acute renal failure.
Preterm premature rupture of membranes is associated with significant risk to the mother and her unborn child. With PPROM remote from term, close clinical observation for infection, placental abruption, onset of labor and fetal compromise is necessary. A case study is presented of a 23 year old G1P0 who presented at 24 weeks with PPROM. Her fetus was breech. At 31 weeks she developed preeclampsia and was treated with magnesium sulfate. Her lab values were montored closely and with the development of HELLP she was delivered by cesarean section. At that time she was also diagnosed with acute renal failure due to acute tubular necrosis. Although rare, preeclampsia can be a cause of acute renal failure. Etiology of preeclampsia, HELLP and acute renal failure are discussed as well as management of the patient including interdisciplinary care and lab values. Outcomes and lessons learned are included.